According to world-renowned Dr. Mehmet Oz (Dr. Oz), “too little vitamin D is our most critical vitamin deficiency. It’s a major risk factor for cancer, autoimmune problems, and heart disease.”  Vitamin D, also called the "sunshine vitamin," has recently received much attention as a needed nutritional supplement to improve human health.  Decreased levels of Vitamin D have been associated with a range of diseases, such as osteoporosis, osteoarthritis, cancer of the breast, cardiovascular disease, and many others.

Vitamin D deficiency also plays a key role in the development of type 1 diabetes.  Vitamin D is needed for islet cells to produce insulin, the hormone that allows cells to take up blood sugar.  Without enough Vitamin D, islet cells don't produce insulin.  Vitamin D also regulates white blood cells that make up the immune system; Vitamin D with calcium has shown to reduce osteoporosis and hip fractures; improves the absorption and utilization of calcium and phosphorus; hardens and repairs bones; prevents rickets, treats hypocalcaemia, and promotes normal growth in children; supports the healthy function of the thyroid gland; may help prevent colon cancer.  It is truly the wonder Vitamin.

Vitamin D is naturally manufactured in the skin, primarily through exposure to sunlight. Most adults require between 1,000-2,000 IU’s of Vitamin D daily.  But getting adequate vitamin D relies on skin exposure to enough sunlight, healthy intestines to absorb it from foods or supplementation, and a healthy liver and kidneys to properly assimilate it into our bodies.  Because most people work indoors and fear direct exposure to sunlight due to skin cancer, few people are able to maintain healthy levels of vitamin D solely through sunlight.

The October 26, 2009 issue of the Archives of Internal Medicine stated “The worldwide prevalence of Vitamin D deficiency is striking and more than 40% of the population may be Vitamin D deficient.”  Vitamin D levels in humans are also affected by geographic location, skin pigmentation, and age.  For example, studies have shown that people with darker skin pigmentation need much more exposure to sunlight to produce the same amount of vitamin D as someone with lighter skin.

Vitamin D is also naturally found in a limited number of foods, such as nuts, eggs, and fish, and it is a common additive in milk and orange juice.  But in order to obtain adequate amounts of vitamin D from food or fortified beverages, pounds of fish or multiple glasses of milk would need to be consumed on a daily basis, which most people are simply unable to do.  And, after the age of 45, the kidneys reduce production of alphahydroxylase, an enzyme that assists in the body's ability to process vitamin D.

The importance of the timing of the proprietary mushroom blend of organic Vitamin D in ImmuSano is further evidenced by a recent statement by the Office of Dietary Supplements, National Institutes of Health, that one of the best sources of Vitamin D is 3 ounces of mushrooms enriched with Vitamin D. 

TNS and Dr. Marvin Hausman have exclusive technological rights under a U.S. Provisional Patent Application which was filed on April 23, 2008 and names Professor Robert B. Beelman, and Graduate Student Michael Kalaras as co-inventors, Department of Food Science, Pennsylvania State University (PSU).

"As a doctor, I receive no greater pleasure than having the opportunity to create products that can help people live longer and healthier lives," stated Marvin S. Hausman MD and Chief Executive Officer of Total Nutraceutical Solutions Inc. (TNS).  "Vitamin D deficiency is worldwide, is implicated in many diseases, and our product have the potential to provide a needed nutritional answer to this problem."

"I am very excited that our new process is being commercially utilized to produce Vitamin D--rich dietary supplements made from the highly nutritious Agaricus blazei mushroom," stated Robert B. Beelman Ph.D., Professor of Food Science, Pennsylvania State University. "I believe this product will be the first of its kind made from a whole food that will appeal to health conscious individuals that desire to consume a plant-based diet."